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PhD student in Biochemistry of Neurodegeneration

ABG-87074 Thesis topic
2019-08-13 > €35,000 and < €45,000 annual gross
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Luxembourg Institute of Health
Dudelange - Luxembourg
PhD student in Biochemistry of Neurodegeneration
  • Biochemistry
Biochemistry, Neurodegeneration, metabolism

Topic description

The Enzymology & Metabolism Research Group (LCSB) and IBBL are looking to hire a PhD student as part of the PARK-QC DTU, an interdisciplinary doctoral training unit focusing on ‘Molecular, Organellar and Cellular Quality Control in Parkinson's disease and Other Neurodegenerative Diseases’ and involving several Luxembourgish biomedical research units.

 In the collaborative project entitled ‘Search for novel PD biomarkers originating from increased molecular damage and/or deficient molecular quality control systems’, the successful PhD candidate will (establish and) analyse cellular and whole organism models of Parkinson’s disease, as well as PD patient-derived material (e.g. plasma, urine, CSF), applying Crispr/Cas9 technology, imaging-based phenotypic approaches and metabolomics techniques.

Main objectives are to find small molecule disease biomarkers and test small molecule-based therapeutic treatments on the cellular/whole organism models.

Starting date

2019-12-02

Funding category

Public/private mixed funding

Funding further details

PArk-QC DTU

Presentation of host institution and host laboratory

Luxembourg Institute of Health

IBBL (Integrated BioBank of Luxembourg), an autonomous institute organised within the Luxembourg Institute of Health (LIH), is a not-for-profit institute dedicated to supporting biomedical research for the benefit of patients. We provide biospecimen-related services and biobanking infrastructure for applied medical research. We are working with the main Luxembourgish actors in translational medicine and with international academic and industry actors.

IBBL’s culture is based on excellence, trust and innovation. Our team is driven by passion and quality.

The University of Luxembourg is a multilingual, international research University. Luxembourg is a dynamic, multicultural country in the heart of Europe with a strong research and development base supported by important organisational resources. The Luxembourg Centre for Systems Biomedicine (LCSB) at the University of Luxembourg offers state-of-the-art facilities and an excellent training environment for early-stage researchers, in particular in the biomedical sciences.

Candidate's profile

Key Skills, Experience and Qualifications

  • Master degree in Biochemistry, Molecular/Cell Biology, Biotechnology, or a related discipline.
  • Strong background in metabolic biochemistry and molecular/cellular biology, as well as good notions in bioinformatics.
  • Previous experience with handling model organisms, mammalian cell culture, mass spectrometry and imaging techniques will be considered as important asset(s).
  • Excellent English writing and speaking skills are essential

We offer

  • Project funding available for up to 48 months
  • Competitive remuneration; contract subject to public national security system benefits
  • A dynamic, exciting and equal opportunity international research environment

 

 

Application deadline

2019-11-01
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