Electroenzymatic Biosensor for H2 Detection

The thesis project focuses on the study of electroenzymatic biosensors without noble metals for the detection of hydrogen (H₂), aimed at mitigating the risks associated with the limited stability range of this gas. In particular, it could involve the detection of H₂ leaks within fuel cell enclosures. This biosensor will leverage the affinity and sensitivity of H₂-specific enzymes. We will explore both the fundamental aspects of the bioelectrode's functioning and its integration into miniaturized devices.

The Bioenergetics and Protein Engineering lab (BIP – UMR 7281) is a Joint Research Unit of the CNRS, under agreement with Aix-Marseille University (AMU).

BIP’s research themes focus on exploring the diversity of energy metabolisms in microorganisms and their applications in the field of bioenergy and the environment. Bringing together biologists, chemists and physicists, the BIP is developing an original approach based on the latest advances in structural genomics, functional proteomics and molecular biophysics. This remarkable multidisciplinarity enables an integrated approach to energy conversion processes, from the physiological level to the molecular bases responsible for the enormous variability of substrates and reactivity in the enzymes and supramolecular structures involved. It also makes it possible to trace the evolution of these systems from the earliest bioenergetic mechanisms to their current diversity.